GW-870086 是一种有效的抗炎剂。 GW-870086 还在糖皮质激素受体激动剂中发挥作用（在表达 NF-κB 的 A549 细胞中 pIC50：10.1）。

PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.

Toceranib 磷酸盐是分裂激酶 RTK 家族多个成员（包括 Flk-1/KDR、PDGFR）酪氨酸激酶活性的选择性抑制剂。